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작성자자연산홍어젓 조회 14회 작성일 2020-09-19 11:47:42 댓글 0


Biological Fate of Artificial Sweeteners | Erythritol & Sorbitol

Did you ever wonder what happens to artificial sweeteners when you consume them in food? In this video, we track the fates of two of them (erythritol and sorbitol). They cause loose stool, but they can have other functions as well.
Law Wren : Great content. I came across this comment and am wondering if you can address the claim regarding erythritol and liver elimination/toxicity: "It is a synthetic plant derivative, a sugar alcohol, with ZERO nutritional value, is a liver a toxin... your liver has to deal with it as a toxin and get it out of the body ASAP just like all other indigestible compounds"

Polyol Pathway and Its Role in Diabetes Pathogenesis

Polyol Pathway and Role in Diabetes Pathogenesis lesson.

What is the purpose of the Polyol (Sorbitol-Aldose Reductase) Pathway, and what is the role of the polyol pathway in diabetes pathogenesis? Here, I explain what the actual function of the polyol pathway is and that during diabetes, I explain how the polyol pathway can lead to diabetic retinopathy, diabetic nephropathy and diabetic neuropathy.


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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.

Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.


*Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.*

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SuperMedBros : Excellent Video Watch our video on Sorbitol Pathway too .

Hussen Qhatni : Thanks for this
Very clear
Mert Selvi : thanks man
Ananya Anurag Anand : Thankyou
TheFenerbahceSK : Isn't the whole problem with diabetes that the insulin receptors don't work so glucose isn't getting into the tissues in the first place? If so, why do we care about this if glucose isn't getting into the tissues?
FATIMA A : thanks alot
ogurimushitaro2 : There is a mistake in the first figure. Aldose reductase only takes aldose form (aldehyde linear) not pyranose form as a substrate.
oshobo : Real shit man, thanks.
Wala Abdeljawad : thank u so much
A. ALzahrani : I love you

Diabetes complication: Sorbitol animation

In normal blood glucose level the glucose is metabolized through hexokinase pathway to TCA cycle to produce ATP. However in hyperglycemic state the hexokinase pathway is saturated and more glucose is diverted into aldose reductase enzyme pathway to produce sorbitol which has strong osmotic effect and drawn fluids into the cells. The flooded cells are ultimately destroyed.
SuperMedBros : Excellent Video Watch our video on Sorbitol Pathway too .

Leena Ghaeb : Thank you, i was very confused but this video clarified my thoughts!




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